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Home / Current Molecular Medicine, Volume 10, Number 7

Open Access From Nanotechnology to Nanomedicine: Applications to Cancer Research

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Authors: Seigneuric, R.; Markey, L.; S.A. Nuyten, D.; Dubernet, C.; T.A. Evelo, C.; Finot, E.; Garrido, C.

Source: Current Molecular Medicine, Volume 10, Number 7, 2010, pp. 640-652(13)

Publisher: Bentham Science Publishers

Scientific advances have significantly improved the practice of medicine by providing objective and quantitative means for exploring the human body and disease states. These innovative technologies have already profoundly improved disease detection, imaging, treatment and patient follow-up. Today's analytical limits are at the nanoscale level (one-billionth of a meter) enabling a detailed exploration at the level of DNA, RNA, proteins and metabolites which are in fact nano-objects. This translational review aims at integrating some recent advances from micro- and nano-technologies with high potential for improving daily oncology practice.





Keywords: Anthracyclins; Antibodies; Antibody; Antigen; Aptamers; Aptasensors; Biomarkers; Biomolecules; Biosensors; Blood-brain barrier; CTC chip; Camptothecin; Cardiotoxicity; Chemotherapy; Clonogenic cancer cells; DNA topoisomerase; Docetaxel; Doxorubicin; Drug delivery; ELISA; EPR effect; Electrophoresis; Ellipsometry; Enzymes; EpCAM(CD326); Epithelial Cell Adhesion Molecule; Factor alpha; Fluorescence microscope; Immune system; Labs-on-chip; Metastases; Microfluidics; Microtechnologies; Myelosuppression; Nano-objects; Nanomedicine; Nanoparticle; Nanoparticles; Nanorods; Nanospheres; Nanotechnology; Nanotubes; Nanovectorization; Nanowires; Paclitaxel; Pharmacokinetics; Point-of-care devices; Radiotherapy; Reactive oxygen species; Reticuloendothelial system; SPR imaging; Surface plasmon resonance; Tumor necrosis; Vectorization; XMT-1001; circulating tumour cell; immunohistochemistry; nanoparticle

Document Type: Research Article

Publication date: 01 October 2010

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  • Current Molecular Medicine is an interdisciplinary journal focused on providing the readership with current and comprehensive reviews on fundamental molecular mechanisms of disease pathogenesis, the development of molecular-diagnosis and/or novel approaches to rational treatment. The reviews should be of significant interest to basic researchers and clinical investigators in molecular medicine. Periodically the journal will invite guest editors to devote an issue on a basic research area that shows promise to advance our understanding of the molecular mechanism(s) of a disease or has potential for clinical applications.
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