Miniaturization of a Panel of High Throughput Yeast-Cell-Based Nuclear Receptor Assays in 384- and 1536-Well Microplates
Keywords: 17-estradiol; AR assay; AhR assays; BMAAREluc/AR; BMAAhR/ ARNT; BMAER; Bentzo-a-pyrene; Biomek NXP; Cell-based assay; D-luciferin; Dihydro- testosterone; ER yeast assay; GraphPad Prism 4; LOD; REACH; Victor3 1420 Multilabel Counter; Z' factor; endocrine-disrupting compounds; estrogen receptor; high throughput assay; high throughput screening; luciferase; nuclear receptors; saccharomyces cerevisiae
Document Type: Research Article
Publication date: 01 January 2011
- Combinatorial Chemistry & High Throughput Screening publishes full length original research articles and reviews describing various topics in combinatorial chemistry (e.g. small molecules, peptide, nucleic acid or phage display libraries) and/or high throughput screening (e.g. developmental, practical or theoretical). Ancillary subjects of key importance, such as robotics and informatics, will also be covered by the journal. In these respective subject areas, Combinatorial Chemistry & High Throughput Screening is intended to function as the most comprehensive and up-to-date medium available. The journal should be of value to individuals engaged in the process of drug discoveryand development, in the settings of industry, academia or government.