A Stoichiometric Model of the Kinetics of Nanoparticle Clusterings Mediated by Antigen-Antibody Interactions
Mass action models have been used to model chemical reactions. We use the methods of stoichiometry to model the formation of nanoparticle clusterings where the bond between the nanoparticles is formed by antibody-antigen-antibody interaction. The growth of such configurations can be
determined and the change of the mean nanoparticle size determined. This model can be used to determine the concentration of antigen in solution.
Keywords: IMMUNOASSAY; MASS-ACTION KINETIC MODEL; NANOPARTICLES; STOICHIOMETRY
Document Type: Research Article
Publication date: 01 September 2011
- Journal of Computational and Theoretical Nanoscience is an international peer-reviewed journal with a wide-ranging coverage, consolidates research activities in all aspects of computational and theoretical nanoscience into a single reference source. This journal offers scientists and engineers peer-reviewed research papers in all aspects of computational and theoretical nanoscience and nanotechnology in chemistry, physics, materials science, engineering and biology to publish original full papers and timely state-of-the-art reviews and short communications encompassing the fundamental and applied research.
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