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Highly Biocompatible Drug-Delivery Systems Based on DNA Nanotechnology

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Nanotechnology has been widely used in pharmacology and medicine, particularly for developing methods to enhance drug bioavailability and reduce the toxic side effects of drugs, and has given rise to the "nano drug-delivery system." Recent work has demonstrated that DNA nanostructures, which can efficiently penetrate cells and are highly biocompatible, hold considerable potential for use in designing effective nano drug-delivery systems. Here, we briefly review the advantages offered by DNA nanostructures for drug delivery, the various types of currently available drug-delivery systems based on DNA nanostructures, and the cellular uptake of DNA nanostructures.
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Keywords: DNA NANOSTRUCTURE; DNA ORIGAMI; DRUG-DELIVERY SYSTEM; NANOTECHNOLOGY

Document Type: Review Article

Publication date: 01 July 2017

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  • Journal of Biomedical Nanotechnology (JBN) is a peer-reviewed multidisciplinary journal providing broad coverage in all research areas focused on the applications of nanotechnology in medicine, drug delivery systems, infectious disease, biomedical sciences, biotechnology, and all other related fields of life sciences.
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