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Home / Comparative Medicine, Volume 64, Number 6

Open Access Pancreatic Carcinoma in an African Clawed Frog (Xenopus laevis)

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Authors: Stern, Adam W 1 ; Allison, Sarah O 2 ; Chu, Caroline 3 ; 

Source: Comparative Medicine, Volume 64, Number 6, December 2014, pp. 421-423(3)

Publisher: American Association for Laboratory Animal Science

This report describes the histologic features of a pancreatic carcinoma in an adult female African clawed frog (Xenopus laevis). The animal was found to be in poor body condition and subsequently euthanized for a complete necropsy. Histologically, the pancreas was effaced by packets of polyhedral cells consistent with a pancreatic islet cell carcinoma. Metastatic disease was not identified. Pancreatic tumors are uncommon in amphibians, and this report is the first to describe a pancreatic carcinoma in an African clawed frog.

Document Type: Case Report

Affiliations: 1: Veterinary Diagnostic Laboratory, University of Illinois, Urbana, Illinois, USA. [email protected] 2: Division of Animal Resources, Illinois, University of Illinois, Urbana, Illinois, USA 3: Department of Pathobiology, University of Illinois, Urbana, Illinois, USA

Publication date: 01 December 2014

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  • Comparative Medicine (CM), an international journal of comparative and experimental medicine, is the leading English-language publication in the field and is ranked by the Science Citation Index in the upper third of all scientific journals. The mission of CM is to disseminate high-quality, peer-reviewed information that expands biomedical knowledge and promotes human and animal health through the study of laboratory animal disease, animal models of disease, and basic biologic mechanisms related to disease in people and animals.

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