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Extreme Hyperferritinemia in Dizygotic Twins With Human Parechovirus-3 Infection

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Human parechovirus-3 has been associated with severe clinical manifestations in infants, such as sepsis-like illness and meningoencephalitis. Nevertheless, the vast majority of patients have a favorable outcome. We report the occurrence of this infection in dizygotic infants with extreme hyperferritinemia and a transient impairment of natural killer cell cytotoxicity.
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Keywords: hemophagocytic lymphohistiocytosis; human parechovirus-3; hyperferritinemia

Document Type: Research Article

Publication date: 2016-12-01

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