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High-Performance Immunosorbents for the Selective Trace Analysis of Emerging Contaminants in Water

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Abstract:

Dissolved micro-constituents such as pesticides, pharmaceuticals, and steroid hormones may be present at parts-per-billion levels or lower in water and are often found complex matrices. Immunosorbents, which make use of immobilized antibodies as selective binding agents, can be attractive tools for the analysis of these contaminants in environmental samples. The advantages of immunosorbents include their high selectivity and strong binding for a target, making these materials ideal for the concentration and pretreatment of analytes in environmental samples. This report will give an overview of several recent applications of high-performance immunosorbents for the trace analysis of micro-constituents in water. Applications will be provided that involve the use of immunosorbents coupled on-line with reversed phase liquid chromatography and mass spectrometry for the detection and analysis of micro-constituents. Examples of analytes that have been examined by these approaches include triazine herbicides, chlorophenoxyacetic acid type herbicides such as 2,4-D, and pharmaceutical agents such as carbamazepine.

Keywords: LC/MS/MS; Micro-constituents; immunosorbents; trace analysis; water

Document Type: Research Article

DOI: https://doi.org/10.2175/193864710798193734

Publication date: 2010-01-01

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  • Proceedings of the Water Environment Federation is an archive of papers published in the proceedings of the annual Water Environment Federation® Technical Exhibition and Conference (WEFTEC® ) and specialty conferences held since the year 2000. These proceedings are not peer reviewed.

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