Elucidating the Role of Nitrifiers versus Heterotrophic bacteria in the Biotransformation of Pharmaceuticals during Wastewater Treatment
Biodegradation of 17α-ethinylestradiol (EE2) was investigated in nitrifying and heterotrophic cultures. Significant removal of EE2 was observed in batch cultures of Nitrosomonas europaea (98% transformation), continuous flow heterotrophic cultures devoid of nitrifiers (OX−; 55-70% mineralization) and a batch nitrifying activated sludge culture (NSR; 60% transformation). EE2 was not transformed in the presence of the OX− culture when grown under batch conditions. Two different metabolites were detected from the continuous flow OX− culture. One of these metabolites appears to coincide with a single metabolite formed by the NSR culture that contained both heterotrophs and nitrifiers. Results from these investigations confirm that EE2 can be transformed via multiple pathways that exist within diverse nitrifying activated sludge.
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Document Type: Research Article
Publication date: 2008-01-01
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