Skip to main content

Application of MBR/Advanced Oxidation Treatment Technologies For the Treatment of Pharmaceutical Wastewaters

Buy Article:

$17.50 plus tax (Refund Policy)

Or sign up for a free trial

Abstract:

This paper presents a case study for the design of a pharmaceutical wastewater treatment plant (WWTP) for the removal of pharmaceutical effluent guideline (PEG) compounds and active pharmaceutical ingredients (APIs) from a pharmaceutical formulation plant effluent. The regulated PEG compounds at this site are acetone, n-amyl acetate, ethyl acetate, isopropyl acetate, and methylene chloride. In addition to meeting the PEG limitations for these compounds the pharmaceutical company desired to reduce the concentrations of APIs in its effluent discharge. Bench scale studies were conducted on the raw wastewater and 10 specific APIs used at the site. The bench scale studies included respirometry and advanced oxidation treatment (AOT) testing. The respirometry treatability testing evaluated the potential for biomass inhibition caused by the APIs and the bio-degradability of the APIs. The AOT testing evaluated the feasibility of destroying the non-biodegradable APIs through oxidation with hydroxyl radicals. The bench scale testing was followed by installation and operation of a 1.0 gpm pilot treatment system consisting of a membrane bioreactor (MBR) and UV/peroxide and UV/ozone AOT processes. Full scale design data for a MBR / AOT wastewater treatment facility was developed based on the pilot plant data. The full scale system consists of equalization, neutralization, membrane bioreactor with hollow fiber microfiltration membranes, and advanced oxidation treatment of the MBR permeate using hydrogen peroxide reactors activated with ultra violet light. The WWTP start-up was completed in August 2006. This paper summarizes the findings from the bench and pilot studies and presents the full scale plant basis of design and performance.

Keywords: ADVANCED OXIDATION; MEMBRANE BIOREACTOR; PHARMACEUTICAL WASTEWATER; TREATABILITY TESTING; TREATMENT

Document Type: Research Article

DOI: https://doi.org/10.2175/193864707787781665

Publication date: 2007-10-01

More about this publication?
  • Proceedings of the Water Environment Federation is an archive of papers published in the proceedings of the annual Water Environment Federation® Technical Exhibition and Conference (WEFTEC® ) and specialty conferences held since the year 2000. These proceedings are not peer reviewed.

    A subscription to the Proceedings of the Water Environment Federation includes access to most papers presented at the annual WEF Technical Exhibition and Conference (WEFTEC) and other conferences held since 2000. Subscription access begins 12 months after the event and is valid for 12 months from month of purchase. A subscription to the Proceedings of the Water Environment Federation is included in Water Environment Federation (WEF) membership.

    WEF Members: Sign in (right panel) with your IngentaConnect user name and password to receive complimentary access. Access begins 12 months after the conference or event
  • Subscribe to this Title
  • Membership Information
  • About WEF Proceedings
  • WEFTEC Conference Information
  • Learn about the many other WEF member benefits and join today
  • Ingenta Connect is not responsible for the content or availability of external websites
  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
X
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more