Recurrent venous thrombosis in a patient with chronic lymphocytic leukemia and acquired protein S deficiency

Authors: Miljić, P.; Milošević-Jovičić, N.; Antunović, P.; Bošković, D.; Basara, N.; Rolović, Z.

Source: Haematologia, Volume 30, Number 1, 2000 , pp. 51-54(4)

Publisher: VSP, an imprint of Brill

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Abstract:

A patient with chronic lymphocytic leukemia and an undetectable plasma level of protein S (PS), associated with recurrent venous thrombosis, is described. The laboratory investigation revealed the concomitant presence of an inhibitor directed to PS and a monoclonal protein in the patient's plasma. After treatment with prednisone and cyclophosphamide both the inhibitor to PS and the monoclonal component disappeared.

Keywords: Protein S inhibitor; venous thrombosis; chronic lymphocytic leukemia

Document Type: Research article

DOI: 10.1163/15685590051129896

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