Retrobulbar Cellular Schwannoma. Two Cases Report and Review of the Literature

Authors: Huang W-T.¹; Chen W-j.¹; Hsu H-C.²; Cheng Y-F.³; Eng H-L.¹

Source: Pathology Research and Practice, Volume 199, Number 3, 1 May 2003 , pp. 171-174(4)

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Abstract:

Cellular schwannoma is a variant of classical schwannoma that is characterized by high cellularity. As it is accompanied by mitotic figures, it is easily mistaken for a malignant neoplasm. However, hyalinized thick-walled blood vessels, an alternating growth pattern of spindle-shaped neoplastic cells, and even Verocay bodies can be found. It is most commonly seen in the paravertebral area, particularly in the mediastinum and retroperitoneum. Retrobulbar cellular schwannoma is uncommon, and only one case has been reported to date. In this study, we report two additional cases of retrobulbar cellular schwannoma that recurred two years after surgery. We suggest that the patient be given an aggressive postoperative treatment because a successful, complete excision cannot be guaranteed at such an anatomic site.

Document Type: Research article

DOI: http://dx.doi.org/10.1078/0344-0338-00371

Affiliations: 1: Department of Pathology, Chang Gung University and Memorial Hospital, Kaohsiung Medical Center, Kaohsiung, Taiwan 2: Department of Ophthalmology, Chang Gung University and Memorial Hospital, Kaohsiung Medical Center, Kaohsiung, Taiwan 3: Department of Radiology, Chang Gung University and Memorial Hospital, Kaohsiung Medical Center, Kaohsiung, Taiwan

Publication date: 2003-05-01