Aggressive Angiomyxoma of the Spermatic Cord. Two Unusual Cases Occurring in Childhood

Authors: Carlinfante G.¹; Marco L.D.²; Mori M.³; Ferretti S.⁴; Crafa P.¹

Source: Pathology Research and Practice, Volume 197, Number 2, February 2001 , pp. 139-144(6)

Buy & download fulltext article:

Price: $29.27 plus tax (Refund Policy)

Abstract:

We report on two cases of aggressive angiomyxoma (AAM) of the spermatic cord occurring in two 13-year-old children. Clinically, the tumor simulated a mass of the spermatic cord. Histologically, it represented a poorly circumscribed, benign myxoid tumor, with a sparse population of stromal cells immunoreactive for vimentin and, focally, for smooth muscle actin. No immunostaining for desmin, S-100, p53, p21^waf-1, c-Erb-B2 and estrogen-progesterone receptors was found. High proliferating cell nuclear antigen (PCNA) immunoexpression found in most of the tumor cells may explain the high risk of recurrence. AAM should be considered in the differential diagnosis of a spermatic cord mass occurring during infancy.

Keywords: Aggressive angiomyxoma; Child; Spermatic cord; Immunohistochemistry

Language: English

Document Type: Miscellaneous

DOI: http://dx.doi.org/10.1078/0344-0338-00025

Affiliations: 1: Dipartimento di Patologia, Università degli Studi di Parma, Italy 2: Divisione di Chirurgia Pediatrica, Azienda Ospedaliera di Parma, Italy 3: Servizio di Anatomia ed Istologia Patologica, Ospedale Ramazzini di Carpi, Italy 4: Divisione di Urologia, Ospedale Ramazzini di Carpi, Italy

Publication date: 2001-02-01