Sonoluminescence optical confocal tomography of tissue

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In this paper, we report experiments on optical confocal tomography by use of sonoluminescence signal in both biological tissue and tissue-simulating media. A high-sensitive confocal scanning setup based on photon counting technique was developed. With the system, we obtained images of the objects embedded in tissue-simulating turbid media. The images showed a high contrast and a lateral resolution of about 100 μm. We finally imaged a carbon stick buried in muscle tissue with the sonoluminescence confocal scanning tomography. This technique has potential applications in clinical diagnosis.

Keywords: Sonoluminescence; confocal tomography; tissue

Document Type: Original Article


Affiliations: 1: Institute of Laser Life Science, South China Normal University, Guangzhou 510631, P. R. China 2: Institute of Laser Science, University of Electro-Communications, 1-5-1 Chofugaoka, Chofu, Tokyo 182-8585, Japan

Publication date: September 1, 2002

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