Control of ciliary motility: A unifying hypothesis
Ciliary motility in ciliates such as Paramecium or Tetrahymena is the mechanism by which cellular behaviour is regulated and on which survival depends. As a consequence, protozoan cilia have elaborate sensing systems built into them, probably by intraciliary transport (ICT-orthologous to intraflagellar transport). As a response to stimuli, 2nd messenger concentration around the axoneme increases. A unifying hypothesis suggests that for rapid responses the 2nd messengers act on axonemal dynein to change the rates of doublet sliding, which in turn affects ciliary parameters that control behaviour.
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Document Type: Research Article
Affiliations: Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA;, Email: email@example.com
Publication date: 2003-12-01