On the mode of action of methionine-enkephalin in inducing hyperglycemia in the fiddler crab Uca lactea annulipes
Authors: Nagaraju, G. Purna Chandra; Sreenivasula Reddy, P.
Source: Bulletin of Marine Science, Volume 70, Number 1, January 2002 , pp. 107-111(5)
Abstract:The possibility that methionine-enkephalin induces hyperglycemia in the fiddler crab, Uca lactea annulipes was investigated. Injection of methionine-enkephalin and FK 33824 (methionine-enkephalin agonist) resulted in significant hyperglycemia in intact crabs but not in eyestalkless crabs. In contrast, naloxone (methionine-enkephalin receptor blocker) significantly (P < 0.0001) decreased hemolymph sugar level in intact crabs. This hyperglycemic action of methionine-enkephalin is hypothesized to be indirect, triggering release of hyperglycemic hormone from the eyestalks of the crabs.
Document Type: Research Article
Publication date: January 1, 2002
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