On the mode of action of methionine-enkephalin in inducing hyperglycemia in the fiddler crab Uca lactea annulipes
The possibility that methionine-enkephalin induces hyperglycemia in the fiddler crab, Uca lactea annulipes was investigated. Injection of methionine-enkephalin and FK 33824 (methionine-enkephalin agonist) resulted in significant hyperglycemia in intact crabs but not in eyestalkless crabs. In contrast, naloxone (methionine-enkephalin receptor blocker) significantly (P < 0.0001) decreased hemolymph sugar level in intact crabs. This hyperglycemic action of methionine-enkephalin is hypothesized to be indirect, triggering release of hyperglycemic hormone from the eyestalks of the crabs.
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Document Type: Research Article
Publication date: 01 January 2002
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