Measurement of aversion to determine humane methods of anaesthesia and euthanasia

Authors: Leach, MC; Bowell, VA; Allan, TF; Morton, DB

Source: Animal Welfare, Volume 13, Supplement 1, February 2004 , pp. 77-86(10)

Publisher: Universities Federation for Animal Welfare

Buy & download fulltext article:

OR

Price: $25.00 plus tax (Refund Policy)

Abstract:

The distress experienced by animals during the induction of unconsciousness remains one of the most important and yet overlooked aspects of effective methods of anaesthesia and euthanasia. Here we show that considerable differences exist in the aversive responses elicited by 12 common methods of inhalational anaesthesia and euthanasia in laboratory rats and mice. Carbon dioxide, either alone or in combination with oxygen or argon, was found to be highly aversive to both species. The least aversive agents were halothane in rats and enflurane in mice. Exposing these animals to carbon dioxide in any form, either for anaesthesia or for euthanasia, is likely to cause considerable pain and distress and is therefore unacceptable when efficient and more humane alternatives are readily available.

Keywords: ANAESTHESIA; ANIMAL WELFARE; AVERSION; CARBON DIOXIDE; EUTHANASIA; RODENT

Document Type: Research Article

Publication date: February 1, 2004

Related content

Tools

Key

Free Content
Free content
New Content
New content
Open Access Content
Open access content
Subscribed Content
Subscribed content
Free Trial Content
Free trial content

Text size:

A | A | A | A
Share this item with others: These icons link to social bookmarking sites where readers can share and discover new web pages. print icon Print this page