Potential Applications and Pitfalls of Bayesian Inference of Phylogeny

Authors: Huelsenbeck J.P.1; Larget B.2; Miller R.E.3; Ronquist F.4

Source: Systematic Biology, Volume 51, Number 5, 1 September 2002 , pp. 673-688(16)

Publisher: Taylor and Francis Ltd

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Abstract:

Only recently has Bayesian inference of phylogeny been proposed. The method is now a practical alternative to the other methods; indeed, the method appears to possess advantages over the other methods in terms of ability to use complex models of evolution, ease of interpretation of the results, and computational efficiency. However, the method should be used cautiously. The results of a Bayesian analysis should be examined with respect to the sensitivity of the results to the priors used and the reliability of the Markov chain Monte Carlo approximation of the probabilities of trees.

Keywords: BAYESIAN INFERENCE; MARKOV CHAIN MONTE CARLO; PHYLOGENY; POSTERIOR PROBABILITY

Document Type: Research article

Affiliations: 1: Section of Ecology, Behavior and Evolution, Division of Biology, University of California–San Diego, La Jolla, CA 92093-0116, USA 2: Department of Mathematics and Computer Science, Duquesne University, Pittsburgh, PA15282, USA 3: Department of Biological Sciences, Southeastern Louisiana University, Hammond, LA 70402, USA 4: Department of Systematic Zoology, Evolutionary Biology Centre, Uppsala University, Norbyv. 18D, SE-752 36 Uppsala, Sweden

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