Authors: Sorichter S.; Mair J.; Koller A.; Muller E.; Kremser C.; Judmaier W.; Haid C.; Calzolari C.; Puschendorf B.

Source: Journal of Sports Sciences, Volume 19, Number 9, 1 September 2001 , pp. 687-691(5)

Publisher: Taylor and Francis Ltd

Abstract:

The aim of this study was to examine the relationship between myosin heavy chain (MHC) release as a specific marker of slow-twitch muscle fibre breakdown and magnetic resonance imaging (MRI) of skeletal muscle injury after eccentric exercise. The effects of a single series of 70 high-intensity eccentric contractions of the quadriceps femoris muscle group (single leg) on plasma concentrations of creatine kinase and MHC fragments were assessed in 10 young male sport education trainees before and 1 and 4 days after exercise. To visualize muscle injury, MRI of the loaded thigh was performed before and 4 days after the eccentric exercise. All participants recorded an increase (P < 0.05) in creatine kinase after exercise. In five participants, T2 signal intensity was unchanged post-exercise compared with pre-exercise and MHC plasma concentration was normal; however, they showed an increase (P < 0.05) in creatine kinase after exercise. For the remaining five participants, there was an increase in T2 signal intensity of the loaded vastus intermedius and vastus lateralis. These changes in MRI were accompanied by an increase in MHC plasma concentration (P < 0.01) as well as an increase in creatine kinase (P < 0.01). We suggest that changes in MRI T2 signal intensity after muscle damage induced by eccentric exercise are closely related to damage to structurally bound contractile filaments of some muscle fibres. Additionally, MHC plasma release indicates that this damage affects not only fast-twitch fibres but also some slow-twitch fibres.

Keywords: CREATINE KINASE; ECCENTRIC EXERCISE; MYOSIN HEAVY CHAINS; MAGNETIC RESONANCE IMAGING

Language: English

Document Type: Research article

Publication date: 2001-09-01

More about this publication?

• Editorial Board
• Information for Authors
• Subscribe to this Title
• ingentaconnect is not responsible for the content or availability of external websites

Related content

• In this: publication
• By this: publisher
• In this Subject: Internal Medicine
• By this author: Sorichter S. ;  Mair J. ;  Koller A. ;  Muller E. ;  Kremser C. ;  Judmaier W. ;  Haid C. ;  Calzolari C. ;  Puschendorf B.

Website © Publishing Technology. Article copyright remains with the publisher, society or author(s) as specified within the article.

• Terms and conditions
• Privacy policy
• Information for advertisers