Anticestodal Activity of Trifolium repens Extract

Authors: Tangpu, Vareishang¹; Temjenmongla, Kumar¹; Yadav, Arun¹

Source: Pharmaceutical Biology (Formerly International Journal of Pharmacognosy), Volume 42, Number 8, December 2004 , pp. 656-658(3)

Publisher: Taylor and Francis Ltd

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Abstract:

Trifolium repens L. is an herbal plant that is used in the folk medicine of the Naga tribes of India as a deworming remedy. This study deals with evaluating its anticestodal activity using experimental Hymenolepis diminuta Rudolphi infections in albino rats. Doses of T. repens aerial shoots extract 200 and 500?mg/kg reduced the mean fecal egg counts of H. diminuta by 47.72% and 54.59% and worm recovery rate by 60.00% and 40.00%, respectively. Praziquantel, the standard cestocidal drug, reduced the mean fecal egg count by 65.90% and worm recovery rate by 26.67%. The study suggests that the aerial shoots of T. repens bear anticestodal properties and supports its use in the traditional medicine system.

Keywords: Anticestodal activity; cestoda; Hymenolepis diminuta; India; traditional medicine; Trifolium repens

Document Type: Research article

DOI: 10.1080/13880200490902617

Affiliations: 1: Department of Zoology, North-Eastern Hill University, Shillong, India

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