Observations on the prevention of cleft palate in dogs by folic acid and potential relevance to humans

Authors: Elwood, JM; Colquhoun, TA

Source: New Zealand Veterinary Journal, Volume 45, Number 6, 1 December 1997 , pp. 254-256(3)

Publisher: Taylor and Francis Ltd

Buy & download fulltext article:

OR

Price: $61.16 plus tax (Refund Policy)

Abstract:



Folic acid has been shown to prevent neural tube defects in humans, but its effects on other defects is unknown. In a consistent breeding programme of Boston terrier dogs started in 1974, folic acid supplementation (5 mg/day) was introduced in 1981. The frequency of cleft palate fell from 9/51 (17.6%) without folic acid to 8/191 (4.2%) after its introduction, giving a reduction of 76% (95% confidence limits 42%-90%, p = 0.003).

Keywords: Congenital disease; Dog; Neurological

Document Type: Short Communication

Publication date: December 1, 1997

More about this publication?
Related content

Key

Free Content
Free content
New Content
New content
Open Access Content
Open access content
Subscribed Content
Subscribed content
Free Trial Content
Free trial content

Text size:

A | A | A | A
Share this item with others: These icons link to social bookmarking sites where readers can share and discover new web pages. print icon Print this page