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Synthesis of Zolmitriptan and Related Substances

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Efficient and cost-effective synthesis of Zolmitriptan 1 employing Japp–Klingemann reaction and a new robust purification strategy is described.

Keywords: Indole derivatives; Japp–Klingemann reaction; serotonin receptor; zolmitripton

Document Type: Research Article

Affiliations: 1: Dr. Reddy's Laboratories, Bachupalli, Qutubullapur, India 2: Department of Chemistry, Institute of Science and Technology, J.N.T University, Hyderabad, India

Publication date: 17 December 2013

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