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One-Step Synthesis and Isolation of N-(tert-Butoxycarbonyl)-N'-methylthiourea on a Large Scale

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Abstract:

Simple preparation and isolation of N-(tert-butoxycarbonyl)-N'-methylthiourea on a large scale are described.

Keywords: 1,5-Dimethy-4,6-dithioxo-[1,3,5]-triazinan-2-one; N-methyl-thiourea; guanidine; methyl isothiocyanate; tert-butyl carbamate

Document Type: Research Article

DOI: http://dx.doi.org/10.1080/00397910802238700

Affiliations: Schering-Plough Research Institute, Kenilworth, New Jersey, USA

Publication date: January 1, 2008

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