LiBr: A Mild Lewis Acid Catalyst for Efficient One-Pot Synthesis of α-Amino Nitriles

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Abstract:

α-Amino nitriles are synthesized in a one-pot, three-component coupling of aldehydes, amines, and trimethylsilyl cyanide using a catalytic amount of LiBr at ambient temperature.

Keywords: LiBr; Strecker nitriles; trimethylsilyl cyanide

Document Type: Research Article

DOI: http://dx.doi.org/10.1080/00397910802213729

Affiliations: Department of Chemistry, Punjabi University, Patiala, Punjab, India

Publication date: January 1, 2008

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