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One-Pot Synthesis of Acid Chloride from 1,2-Diols

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A simple and mild system for 1,2-diol cleavage has been developed using a combination of lead diacetate and tert-butyl hypochlorite at room temperature.

Keywords: 1,2-diols; acid chlorides; aldehydes; lead(II) acetate; tert-butyl hypochlorite

Document Type: Research Article

Affiliations: Department of Pharmaceutical Sciences and Technology, University Institute of Chemical Technology, University of Mumbai, Matunga, Mumbai, India

Publication date: 01 January 2007

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