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Home / Synthetic Communications, Volume 36, Number 15

Facile One‐Pot Synthesis of 3‐{2‐[5‐Hydroxy‐4‐(2‐hydroxy‐ethyl)‐3‐methyl‐pyrazol‐1‐yl]‐thiazol‐4‐yl}‐chromen‐2‐ones via a Three‐Component Reaction

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Authors: Rajeswar Rao, V.; Vijaya Kumar, P.

Source: Synthetic Communications, Volume 36, Number 15, 2006, pp. 2157-2161(5)

Publisher: Taylor and Francis Ltd

DOI: https://doi.org/10.1080/00397910600637012

Reaction of 3‐(2‐bromo‐acetyl)‐chromen‐2‐one with thiosemicarbazide and 2‐acetylbutyro lactone in anhydrous ethanol gave 3‐{2‐[5‐hydroxy‐4‐(2‐hydroxy‐ethyl)‐3‐methyl‐pyrazol‐1‐yl]‐thiazol‐4‐yl}‐chromen‐2‐one in good yields.

Keywords: 2‐Acetylbutyrolactone; benzopyran‐2‐one; pyrazoles; thiazoles

Document Type: Research Article

Affiliations: Department of Chemistry, National Institute of Technology, Warangal, India

Publication date: 01 January 2006

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