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Study on Ultrasonic Extraction of Gastrodin from Gastrodia elata Bl.

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Gastrodin, a pharmacologically active constituent, was ultrasonically extracted from gastrodia elata Bl. in the aqueous solution. The effects of six parameters including ethanol-water compositions, extraction time, extraction temperature, particle size, solvent volume, and ultrasonic power on the extraction yield of gastrodin were investigated. According to the orthogonal design, the optimal extraction conditions was explored as extraction temperature 60°C, extraction time 50 minutes, ultrasonic power 126 W, solvent volume 8 mL · g-1, ethanol-water compositions 70%, and particle size 10-20 mesh. Though the yield of gastrodin via ultrasonic extraction was about 0.01% lower than that from the reflux extraction, the extraction time of the ultrasonic extraction was greatly shortened. Therefore, ultrasonic extraction has high efficiency and is proved to be very valuable in the extraction of gastrodin from gastrodia elata Bl.

Keywords: Gastrodia elata Bl; Gastrodin; orthogonal design; ultrasonic extraction

Document Type: Research Article

DOI: http://dx.doi.org/10.1080/01496390903566671

Affiliations: Department of Medicine, China Pharmaceutical University, Nanjing, People's Republic of China

Publication date: January 1, 2010

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