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Antioxidant and Antibacterial Activity of Nutraceutical Compounds from Chlorella vulgaris Extracted in Hydrothermal Condition

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Water in hydrothermal condition has been used for extraction of nutraceutical compounds from Chlorella vulgaris. Hydrothermal extraction was carried out in a semi-batch and a batch extractor at various temperatures (120-200°C), pressures (2-10 MPa), and extraction times (30-300 min) to extract antioxidant and antibacterial compounds. The effect of extraction condition on the yield of extract was investigated. The antioxidant and antibacterial activity of extracts obtained by hydrothermal extraction were examined. The increasing extraction temperature resulted in higher antioxidant activity, but lower antimicrobial activity. As comparison with hot water extraction, the antioxidant activity of extract obtained by hydrothermal extraction was higher than that obtained by hot water extraction, but the antibacterial activity of the extract obtained by hydrothermal extraction was lower.

Keywords: Antimicrobial activity; Chlorella vulgaris; antioxidant activity; hydrothermal extraction

Document Type: Research Article


Affiliations: 1: Graduate School of Science and Technology, Kumamoto University, Kurokami, Kumamoto, Japan 2: Bioelectric Research Center, Kumamoto University, Kurokami, Kumamoto, Japan,Chemical Engineering Department, Sepuluh Nopember Institute of Technology, Kampus ITS Keputih, Sukolilo, Surabaya, Indonesia 3: Bioelectric Research Center, Kumamoto University, Kurokami, Kumamoto, Japan 4: Chlorella Industry Co., Ltd., Chikugoshi, Fukuoka, Japan

Publication date: 2009-01-01

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