@article {Teijeiro:Number 2/January 2006:1525-7770:191,
	author = "Teijeiro, Silvina",
	author = "Brinon, Margarita",
	title = "3-Azido-3-Deoxy-5-O-Isonicotinoylthymidine: A Novel Antiretroviral Analog of Zidovudine. III. Solubility Studies",
	journal = "Nucleosides, Nucleotides & Nucleic Acids",
	volume = "25",
	year = "Number 2/January 2006",
	abstract = "The pH-solubility behavior and solubility of 3'-azido-3'-deoxy-5'-O-isonicotinoylthymidine (AZT-Iso), an antiretroviral derivative of zidovudine with important biological activity, was studied in water, ethanol, ethanol: water, and n-octanol. The N-pyridine pKa value was determined from its pH-solubility profile, which was in accordance with that of the experimental value of methyl isonicotinate. Also, the ethanol cosolvency in ethanol:water mixtures at 25°C was studied, and log-linear and nonlinear solubilization models were applied to the experimental solubility AZT-Iso data, which allowed us to predict its solubility in those solvent mixtures at a determined content of cosolvent.",
	pages = "191-202(12)",
	url = "http://www.ingentaconnect.com/content/tandf/lncn/2006/00000025/00000002/art00005"
	doi = "doi:10.1080/15257770500446964"
}