Effects of cigarette and biomass smoke exposure on oxidant–antioxidant status in rabbits

Authors: Sezer, Murat¹; Fidan, Fatma¹; Koken, Tulay²; Serteser, Mustafa²; Unlu, Mehmet¹

Source: Toxicological and Environmental Chemistry, Volume 88, Number 1, January–March 2006 , pp. 169-174(6)

Buy & download fulltext article:

Price: $56.94 plus tax (Refund Policy)

Abstract:

To evaluate the effects of cigarette smoking and biomass (dried dung) smoke on the oxidant–antioxidant status, three groups each with 5 rabbits were used. Groups of rabbits were exposed to either cigarette smoke, dried dung smoke or dry air, 1h daily for one month. Protein carbonyls, prostaglandin F 2α and malondialdehyde levels were significantly increased and protein sulfhydryls levels were significantly decreased in the cigarette smoke group compared with the control group. Only protein sulfhydryls levels were significantly decreased in dung group compared with the control group. Short course exposure to both cigarette smoke and biomass smoke decreased plasma antioxidant levels but only cigarette smoke increased plasma oxidant levels, whereas biomass smoke did not produce any change.

Keywords: Cigarette smoke; biomass smoke; antioxidant; rabbit

Document Type: Research article

DOI: http://dx.doi.org/10.1080/02772240500233345

Affiliations: 1: Department of Pulmonary Medicine, School of Medicine, Afyon Kocatepe University, Afyon, Turkey 2: Department of Biochemistry, School of Medicine, Afyon Kocatepe University, Afyon, Turkey

Publication date: 2006-01-01