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Accelerating column chromatography: the bundled approach

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The use and construction of a novel apparatus for a variant of conventional column chromatography is described. Relative to a single large conventional column, a bundled apparatus facilitates scale-up by accelerating fraction collection. The bundled approach permits prior knowledge of total running time, total solvent volume, and product location.

Keywords: Bundled apparatus; Column chromatography; Organic synthesis

Document Type: Research Article

Affiliations: Department of Chemistry, Mount Allison University, Sackville, New Brunswick, Canada, E4L 1G8

Publication date: 01 February 2005

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