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One-Pot Synthesis of 2-Arylthiazolines with 1-Butyl-3-Methylimidazolium Tribromide as a Catalytic Reagent

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A simple, inexpensive, and efficient one-pot synthesis of 2-arylthiazoline derivatives under solvent-free conditions using a catalytic amount of 1-butyl-3-methylimidazolium tribromide with excellent product yields is reported. This methodology provides easy, quantitative access to various 2-arylthiazoline derivatives, using environmentally benign 1-butyl-3-methylimidazolium tribromide as a catalyst.

Keywords: 1-butyl-3-methylimidazolium tribromide; 2-Arylthiazolines; 2-aminoethanethiol; nitriles; solvent-free synthesis

Document Type: Research Article

Affiliations: School of Pharmacy,Xinxiang Medical University, Xinxiang,Henan, China

Publication date: 01 March 2012

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