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Home / Phosphorus, Sulfur, and Silicon and the Related Elements, Volume 180, Number 11

Phase-Transfer Catalyzed Alkylation and Cycloalkylation of 2-Mercaptoquinazolin-4(3H)-One

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Author: Khalil, A.

Source: Phosphorus, Sulfur, and Silicon and the Related Elements, Volume 180, Number 11, November 2005, pp. 2533-2541(9)

Publisher: Taylor and Francis Ltd

DOI: https://doi.org/10.1080/104265090929940

Solid/liquid phase-transfer catalyzed alkylation of 2-mercaptoquinazolin-4(3H)-one at 25°C by different organohalogen compounds in the presence of tetrabutylammonium bromide as a catalyst underwent, exclusively, S-monoalkylation or S- and N-, di-, or cycloalkylation, depending on the nature of alkylating agents.

Keywords: Alkylation; cycloalkylation; mercaptoquinazolinone; phase-transfer catalysis

Document Type: Research Article

Affiliations: Chemistry Department, Ain Shams University, Abbasia, Cairo, Egypt

Publication date: 01 November 2005

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