Hypoglycaemic activity of two spices extracts: Rhus coriaria L. and Bunium persicum Boiss

Authors: Giancarlo§, Statti¹; Rosa§, Loizzo Monica¹; Nadjafi, Farsad²; Francesco, Menichini¹

Source: Natural Product Research, Volume 20, Number 9, 20 July 2006 , pp. 882-886(5)

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Abstract:

The hypoglycaemic efficacy of sumac ( Rhus coriaria L.) and black cumin ( Bunium persicum Boiss) extracts were investigated through inhibition of a glycoside hydrolase: α-amylase. On the basis of our result ethyl acetate extract of sumac may have interest in the treatment and prevention of hyperglycaemia, diabetes and obesity, with an IC 50 value of 28.7µgmL −1 .

Keywords: Hypoglycaemic activity; α-Amylase inhibitors; Plant extracts; Sumac ( Rhus coriaria L.); Black Persian cumin ( Bunium persicum Boiss)

Document Type: Research article

DOI: http://dx.doi.org/10.1080/14786410500520186

Affiliations: 1: Department of Pharmaceutical Sciences, University of Calabria, I-87036 Rende (CS), Italy 2: Department of Agronomy, College of Agriculture, Ferdowsi University of Mashhad, Mashhad, Iran

Publication date: 2006-07-20