Steroids and alkaloids from the South China Sea sponge Axinella sp.
A new steroid 24-methylcholasta-1,8,14,22,25-penten-3-one-5α-ol (1) and a new alkaloid 1-(1H-indol-3-yl)-2,3-dihydroxy-5-methyl-hexane (2), together with four known compounds, were isolated from the EtOH extract of the South China Sea sponge Axinella sp. The structures of 1 and 2 were determined on the basis of extensive spectroscopic analysis, including 1D and 2D NMR spectral data.
Keywords: 1-(1H-indol-3-yl)-2,3-dihydroxy-5-methyl-hexane; 24-methylcholasta-1,8,14,22,25-penten-3-one-5α-ol; Axinella sp; alkaloid; sponge; steroid
Document Type: Research Article
Affiliations: 1: Key Laboratory of Marine Bio-resources Sustainable Utilization/Guangdong Key Laboratory of Marine Materia Medica, South China Sea Institute of Oceanology, The Chinese Academy of Sciences, Guangzhou, China 2: Guangzhou Jinan Biomedicine Research and Development Center, Guangzhou, China
Publication date: 01 December 2009
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