Secoiridoids and xanthones from Tylophora secamonoides Tsiang

Authors: Yao, Sheng; Tang, Chun-Ping; Ye, Yang

Source: Journal of Asian Natural Products Research, Volume 10, Number 6, June 2008 , pp. 591-596(6)

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Abstract:

A new secoiridoid, secamonoide A (1), and a new xanthone glycoside, secamonoide B (2), together with nine known compounds, were isolated from the aerial parts of Tylophora secamonoides Tsiang. Their structures were elucidated on the basis of spectroscopic methods. An antimicrobial bioassay showed that secamonoides A and B exhibited weak activities (MIC values greater than 100 mg/ml) against some hospital bacteria in vitro.

Keywords: Tylophora secamonoides Tsiang; Asclepiadaceae; secamonoide A; secamonoide B; antimicrobial activity

Document Type: Research article

DOI: http://dx.doi.org/10.1080/10286020801996184

Affiliations: 1: State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China

Publication date: 2008-06-01