Combined Influence of Barium Sulfate Content and Co-monomer Concentration on Properties of PMMA Bone Cements for Vertebroplasty

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Abstract:

In this work, the combined influence of barium sulfate content and co-monomer concentration on the properties of acrylic bone cement for percutaneous vertebroplasty (PVP) was investigated using a response surface methodology. Cements were prepared with methyl methacrylate (MMA) and either diethyl amino ethyl methacrylate (DEAEM) or dimethyl amino ethyl methacrylate (DMAEM) as co-monomer in the liquid phase, while variable amounts of barium sulfate were incorporated to the solid phase in order to improve the radiopacity of cements. It was found that various properties such as peak temperature, setting time, residual monomer content, mechanical properties and injectability, had an effect on the occurrence of interactions (combined effect) between the barium sulfate and DEAEM in bone cements formulations when independent variables were at their maximum.

Keywords: ACRYLIC BONE CEMENT; AMINO METHACRYLATES; BARIUM SULFATE; INJECTABILITY; VERTEBROPLASTY

Document Type: Research Article

DOI: http://dx.doi.org/10.1163/092050610X516780

Affiliations: 1: Centro de Investigación Científica de Yucatán, A.C., Unidad de Materiales, Calle 43 No. 130, Col. Chuburná de Hidalgo. C.P. 97200, Mérida, Yucatán, México 2: Centro de Investigación Científica de Yucatán, A.C., Unidad de Materiales, Calle 43 No. 130, Col. Chuburná de Hidalgo. C.P. 97200, Mérida, Yucatán, México., Email: manceruc@cicy.mx 3: Instituto de Ciencia y Tecnología de Polímeros, Consejo Superior de Investigaciones Científicas (CSIC), Juan de la Cierva No. 3, 28000 Madrid, Spain

Publication date: January 1, 2011

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