Effect of toluene extraction on Biomer™ surface: I. ESCA, ATR/FTIR, contact angle analysis and biological properties

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Abstract:

Biomer™ is a poly(ether-urethane-urea) block copolymer widely used as biomedical devices. Extraction process of this polymer has purified its surface of low molecular weight polyurethane chains and Santowhite Powder additive. ESCA and ATR/FTIR have suggested a homogenization of the polymer by enrichment of the first layers with poly(aminomethacrylate) additive after extraction. Therefore, the surface of the extracted Biomer™ exhibits a different wettability and biological response. The treatment causes a significant decrease in fibronectin adsorption and induces a reduction in Staphylococcus aureus adhesion.

Keywords: Biomer™; Polyurethane extraction; fibronectin adsorption; surface characterization

Document Type: Research Article

DOI: http://dx.doi.org/10.1163/156856295X00823

Affiliations: 1: Group of Applied Physics, University of Geneva, 20 rue de l'Ecole de Medecine, 1211 Geneva 4, Switzerland 2: Group of Applied Physics, University of Geneva, 20 rue de l'Ecole de Medecine, 1211 Geneva 4, Switzerland, Division of Infectious Disease, University Hospital of Geneva, 1211 Geneva 4, Switzerland 3: Department of Chemistry, University of Siena, Pian dei Mantellini 44, 53100 Siena, Italy 4: Department of Materials, Federal Institute of Technology, 1015 Lausanne, Switzerland 5: Division of Infectious Disease, University Hospital of Geneva, 1211 Geneva 4, Switzerland

Publication date: January 1, 1996

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