Integrated Risk Assessment -- Results from an International Workshop
Abstract:The World Health Organization's International Programme on Chemical Safety and international partners have developed a framework for integrated assessment of human health and ecological risks and four case studies. An international workshop was convened to consider how ecological and health risk assessments might be integrated, the benefits of and obstacles to integration, and the research and mechanisms needed to facilitate implementation of integrated risk assessment. Using the case studies, workshop participants identified a number of opportunities to integrate the assessment process. Improved assessment quality, efficiency, and predictive capability were considered to be principal benefits of integration. Obstacles to acceptance and implementation of integrated risk assessment included the disciplinary and organizational barriers between ecological and health disciplines. A variety of mechanisms were offered to overcome these obstacles. Research recommendations included harmonization of exposure characterization and surveillance methods and models, development of common risk endpoints across taxa, improved understanding of mechanisms of effect at multiple scales of biological organization, and development of methods to facilitate comparison of risks among endpoints.
Document Type: Research Article
Affiliations: 1: U.S. Environmental Protection Agency, Office of Research and Development, National Health and Environmental Effects Research Laboratory, 27 Tarzwell Drive, Narragansett, RI 02882, USA. 2: U.S. Environmental Protection Agency, Office of Research and Development, National Center for Environmental Assessment, 26 W. Martin L. King Drive, MC-117, Cincinnati, OH 45268, USA. 3: World Health Organization, Interregional Research Unit, P.O. Box 12233, MD EC-10, Research Triangle Park, NC 27709, USA. 4: Institute for Risk Assessment Sciences (IRAS), Utrecht University, PO Box 80176, NL-3508 TD Utrecht, The Netherlands. 5: U.S. Environmental Protection Agency, Office of Research and Development, National Health and Environmental Effects Research Laboratory, NHEERL Building, MD-51, Research Triangle Park, NC 27711, USA. 6: European Commission Joint Research Centre, Environment Institute, TP 460, I-21020 Ispra (VA), Italy
Publication date: January 1, 2003