Bioactivity and Structure of Biophenols as Mediators of Chronic Diseases

Authors: Tucker, Gregory¹; Robards, Kevin²

Source: Critical Reviews in Food Science and Nutrition, Volume 48, Number 10, November 2008 , pp. 929-966(38)

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Abstract:

Biophenols and their associated activity have generated intense interest. Current topics of debate are their bioavailability and bioactivity. It is generally assumed that their plasma concentrations are insufficient to produce the health benefits previously attributed to their consumption. However, data on localized in vivo concentrations are not available and many questions remain unanswered. Potential mechanisms by which they may exert significant bioactivity are discussed together with structure activity relationships. Biophenols are highly reactive species and they can react with a range of other compounds. Products of their reaction when functioning as antioxidants are examined.

Keywords: antioxidant; bioactivity; dietary intake; reaction products

Document Type: Research article

DOI: http://dx.doi.org/10.1080/10408390701761977

Affiliations: 1: School of Biosciences, University of Nottingham, Loughborough, Leics, UK 2: School of Science and Technology, Charles Sturt University, Wagga, Wagga, Australia

Publication date: 2008-11-01