Authors: Braverman, Albert S.; Nehra, Anupama; Olowokure, Olugbenga; Raftery, Thomas; Gillette, Peter; Weedon, Jeremy; Olivier, Tracy; Belyayeva, Irina; Deitch, Jonathan

Source: Journal for Vascular Ultrasound, Volume 32, Number 2, June 2008 , pp. 79-81(3)

Publisher: Society for Vascular Ultrasound

Abstract:

Chronic or recurrent leg ulceration occurs in at least 25% of patients with sickle cell disease (SSD). Conflicting data exist concerning the association between SSD leg ulcers and axial venous insufficiency. To determine whether the incidence of perforator vein insufficiency (PVI) is greater in the ulcerated legs of SSD patients than in those without ulcers, the legs of 46 SSD patients, 25 of whom had chronic ulceration and of 19 normal young adult volunteers, were investigated with color-flow venous duplex Doppler sonography. PVI was found in 25 of 37 ulcerated legs and in 14 of 55 nonulcerated legs of SSD patients. The difference was significant (odds ratio 6.2). PVI may contribute to leg ulceration in SSD disease.

Document Type: Research article

Publication date: 2008-06-01

More about this publication?

• The Journal for Vascular Ultrasound (JVU) is the official journal of the Society for Vascular Ultrasound. It consists of original scientific and educational articles, case studies, book reviews, technical reviews, ultrasound principle reviews, viewpoints, letters to the editor, and CME tests. Regular reading of JVU, published quarterly, will keep you current in your field and provide essential information that can be applied in your practice.
  
  Previously known as the Journal of Vascular Technology - View Volumes 16-26 here
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