Macro and Microvascular Effects of Hyperglycemia in Type 2 Diabetic Patients
Author: Bongiovanni, Cheryl M.
Source: Journal for Vascular Ultrasound, Volume 32, Number 1, March 2008 , pp. 14-16(3)
Publisher: Society for Vascular Ultrasound
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Abstract:
The incidence of obesity and diabetes in the United States and worldwide is increasing at alarming rates. A concomitant 2- to 4-fold risk for development of cardiovascular disease accompanies this epidemic. Despite intense interest and a growing body of research, the long-term impact of dietary carbohydrate type, especially sucrose, on insulin resistance and the development of diabetes and atherosclerosis is not established. Insulin resistance is a primary feature of type 2 diabetes and heralds impending glucose intolerance as well as being an independent risk factor for atherosclerotic vascular disease. It follows that reduction of insulin resistance would diminish the risk of development of diabetes and arterial occlusive disease. In developed countries especially, excessive fat and sugar consumption is common and may predispose to the development of diabetes. Lifestyle modification, including caloric restriction, weight loss, and increased physical activity, can reduce insulin resistance, type 2 diabetes, and atherosclerosis. However, no consistent association between dietary carbohydrate type (i.e., simple versus complex carbohydrates) and the risk of diabetes has been elucidated.Document Type: Research article
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