Validation of an Automated Computerized Analyzing System for Measuring Common Carotid Artery Intima–Media Thickness by Brightness Mode Ultrasound

Authors: Fritz, Helmuth F.; Jutzy, Roy V.; Bansal, Ramesh; Housten-Feenstra, Linda

Source: Journal for Vascular Ultrasound, Volume 29, Number 1, March 2005 , pp. 21-26(6)

Publisher: Society for Vascular Ultrasound

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Abstract:

Background and Purpose.—Evaluation of subclinical atherosclerosis by B-mode carotid ultrasound intima–media thickness (IMT) is an endorsed technique whose ease and precision is improved by use of automated IMT measurement algorithms. We report results of a validation study of SonoCalc, an automated IMT software program.

Methods.—Three vascular sonographers measured the mean common carotid artery IMT twice of 120 near and far wall CCA segments from 30 subjects by manual electronic instrument calipers and with SonoCalc.

Results.—Accuracy analysis indicated the equivalence of SonoCalc IMT measurements to those with manual electronic instrument calipers (p < 0.0001). The coefficient of variation (CV) was calculated for each set of duplicate SonoCalc and manual electronic instrument calipers measurements. The average SonoCalc-manual electronic instrument calipers CV differences significantly favored SonoCalc (p < 0.0001).

Conclusion.—This study demonstrated that the use of the SonoCalc and the manual electronic instrument calipers produced measurements whose differences were statistically insignificant. Furthermore, the analysis to assess reproducibility of the two methods showed that the SonoCalc method was significantly more reproducible than the manual electronic instrument calipers methods.

Document Type: Research article

Publication date: 2005-03-01

More about this publication?
  • The Journal for Vascular Ultrasound (JVU) is the official journal of the Society for Vascular Ultrasound. It consists of original scientific and educational articles, case studies, book reviews, technical reviews, ultrasound principle reviews, viewpoints, letters to the editor, and CME tests. Regular reading of JVU, published quarterly, will keep you current in your field and provide essential information that can be applied in your practice.

    Previously known as the Journal of Vascular Technology - View Volumes 16-26 here
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