If you are experiencing problems downloading PDF or HTML fulltext, our helpdesk recommend clearing your browser cache and trying again. If you need help in clearing your cache, please click here . Still need help? Email help@ingentaconnect.com

How half a century of research was required to understand bacterial growth on C1 and C2 compounds; the story of the serine cycle and the ethylmalonyl-CoA pathway

$43.00 plus tax (Refund Policy)

Or sign up for a free trial

Buy Article:

Abstract:

For bacterial growth on substrates with only one or two carbon atoms, special assimilation pathways are required. In 1957, the glyoxylate cycle of Kornberg and Krebs was described for bacterial growth on C2 compounds such as ethanol and acetate. However this pathway did not operate in some photosynthetic bacteria and in some methylotrophs when they were growing on C2 compounds, so an alternative pathway must exist. By 1973 Quayle's serine cycle had been described for methylotrophs growing on C1 compounds such as methanol, but the pathway was incomplete, the unknown part also functioning during growth on C2 compounds. After more than 35 further years of research, the ethylmalonyl-CoA (EMC) pathway for growth on C2 compounds, of photosynthetic bacteria has recently been elucidated. This pathway also operates in methylotrophs during growth on C2 compounds, and on C1 compounds by way of the serine cycle. This review is a celebration of half a century of research and of the fascinating result of that research.
More about this publication?
  • SCIENCE PROGRESS has for over 100 years been a highly regarded review publication in science, technology and medicine. Its objective is to excite the readers' interest in areas with which they may not be fully familiar but which could facilitate their interest, or even activity, in a cognate field. Science Progress commissions world authorities to contribute articles on the most interesting, important and meaningful topics - ranging from cosmology to the environment - and ensures that they are presented for the most effective use of those in both academia and industry.

    Truly, Science Progress publishes an eclectic mix of articles that no library can afford to be without.

    Science Reviews is offering a free trial to Science Progress for the whole of 2014.
  • Editorial Board
  • Information for Authors
  • Subscribe to this Title
  • ingentaconnect is not responsible for the content or availability of external websites
Related content

Tools

Favourites

Share Content

Access Key

Free Content
Free content
New Content
New content
Open Access Content
Open access content
Subscribed Content
Subscribed content
Free Trial Content
Free trial content
Cookie Policy
X
Cookie Policy
ingentaconnect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more