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An overview of the processes shaping protein evolution

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Abstract:

From a comparatively small number of protein structural domains a staggering array of structural variants has evolved which has, in turn, facilitated an expanse of functional derivatives. Herein I review the primary mechanisms which have contributed to the vastness of our existing, and expanding, protein repertoires.

Keywords: CIRCULAR PERMUTATION; COMBINATION; DIVERGENCE; EVOLUTION; GENE DUPLICATION; PROTEIN DOMAINS

Document Type: Research Article

DOI: http://dx.doi.org/10.3184/003685009X12605492662844

Publication date: March 1, 2010

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