Free Content Comparative biology of γδ T cells

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Abstract:

Accumulative evidence suggests that resident γδ T cells in epithelia are biologically distinct from systemic γδ T cells in the circulation. Murine resident γδ T cells have innate immune characteristics and play an important role in tissue homeostasis after damages. In contrast, a unique subset of circulating γδ T cells in primates, like αβ T cells, can mount adaptive immune responses in infections. This article compares biological features between resident and circulating γδ T cells.

Document Type: Research Article

DOI: http://dx.doi.org/10.3184/003685002783238762

Affiliations: zchen@caregroup.harvard.edu

Publication date: November 15, 2002

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