Convenient synthesis and reactions of some 7,9-dimethylthieno-[2,3-b:4,5-b']dipyridines

Authors: Kamal El-Dean, Adel M.; Micky, Gehan Ahmed Ali; Ahmed, Abo Bakr Abdel-Hadi; Ahmed, Rasha Hassan

Source: Journal of Chemical Research, Volume 2009, Number 10, October 2009 , pp. 649-652(4)

Publisher: Science Reviews 2000 Ltd

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Abstract:

3-Amino-4,6-dimethylthieno[2,3-b]pyridine-2-carboxaldehyde was prepared and from it various functionalised thieno[2,3-b:4,5-b']dipyridines were synthesised, using the Friedländer and related reactions. Ethyl 2,7,9-trimethylthieno[2,3-b:4,5-b']dipyridine-3-carboxylate was transformed into a variety of thieno[2,3-b:4,5-b']dipyridine systems with heterocyclic rings attached at C-3 or fused at C2-C3.

Keywords: PYRAZOLES; 1,3,4-OXADIAZOLES; FUSED PYRIDINES; THIOPHENES; PYRROLES; QUINOLINES; PYRIDAZINES; FRIEDLÄNDER REACTIONS

Document Type: Research article

DOI: http://dx.doi.org/10.3184/030823409X12532880131016

Publication date: 2009-10-01

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The Journal of Chemical Research is a monthly journal which has a broad international authorship and publishes research papers and reviews in all branches of experimental chemistry.
Recent papers have described new synthetic methods, new heterocyclic compounds, new natural products, and the inorganic chemistry of metal complexes. Now in its 34th year, the Journal of Chemical Research was established in 1977 as a joint venture by the British, French and German chemical societies and maintains the high standards set by the founding societies. Each paper is independently peer reviewed and only carefully evaluated contributions are accepted.
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