An efficient synthesis of N,N-bis[2-(2-nitrophenylamino)ethyl]glycine glycosyl esters and antiviral activity

Authors: Chen, Hong; Huang, Si-Qing; Xie, Jian-Ying

Source: Journal of Chemical Research, Volume 2008, Number 8, August 2008 , pp. 486-488(3)

Publisher: Science Reviews 2000 Ltd

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Abstract:

N,N-bis[2-(2-nitrophenylamino)ethyl]glycine glycosyl esters were synthesised in good yields at room temperature using DMAP/Et₃N. All of the new synthesised compounds were of β-configuration. The compounds show good antiviral activity against tobacco mosaic virus(TMV).

Keywords: N,N-BIS[2-(2-NITROPHENYLAMINO)ETHYL]GLYCINE; GLYCOSYL ESTERS; DMAP/ET3N

Document Type: Research article

DOI: http://dx.doi.org/10.3184/030823408X338675

Publication date: 2008-08-01

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The Journal of Chemical Research is a monthly journal which has a broad international authorship and publishes research papers and reviews in all branches of experimental chemistry.
Recent papers have described new synthetic methods, new heterocyclic compounds, new natural products, and the inorganic chemistry of metal complexes. Now in its 34th year, the Journal of Chemical Research was established in 1977 as a joint venture by the British, French and German chemical societies and maintains the high standards set by the founding societies. Each paper is independently peer reviewed and only carefully evaluated contributions are accepted.
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