Preparation, X-ray structure and propylaminolysis of 7,7-dichloro-5,7-dihydro-thieno[3,4-b]pyridin-5-one

Authors: Theodorus van Es,; Staskun, Benjamin; Fernandes, Manuel A.

Source: Journal of Chemical Research, Volume 2007, Number 6, June 2007 , pp. 373-376(4)

Publisher: Science Reviews 2000 Ltd

Buy & download fulltext article:

Price: $26.00 plus tax (Refund Policy)

Abstract:

Refluxing 2-methylpyridine-3-carboxylic acid with thionyl chloride for 6-7 h gave (≊50%) title compound dichlorothienolactone 2 as was confirmed by a X-ray structure analysis. The propylaminolysis of 2 provides a new and convenient access to highly functionalised pyrrolo[3,4-b]pyridine derivatives.

Keywords: 7,7-DICHLORO-5,7-DIHYDROTHIENO[3,4-B]PYRIDIN-5-ONE, X-RAY STRUCTURE, 3,3-DICHLORO-4-ETHYLTHIENO[3,4-B]QUINOLINE-1,9-DIONE, DERIVATIVES, REACTION MECHANISMS

Document Type: Research article

DOI: http://dx.doi.org/10.3184/030823407X225392

Publication date: 2007-06-01

More about this publication?

The Journal of Chemical Research is a monthly journal which has a broad international authorship and publishes research papers and reviews in all branches of experimental chemistry.
Recent papers have described new synthetic methods, new heterocyclic compounds, new natural products, and the inorganic chemistry of metal complexes. Now in its 34th year, the Journal of Chemical Research was established in 1977 as a joint venture by the British, French and German chemical societies and maintains the high standards set by the founding societies. Each paper is independently peer reviewed and only carefully evaluated contributions are accepted.
Editorial Board
Subscribe to this Title
ingentaconnect is not responsible for the content or availability of external websites