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Free Content A novel facile one-pot synthesis of 3,1-benzoxazine derivatives

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Abstract:

The synthesis of 3,1-benzoxazine derivatives by the cyclocondensation of substituted o-aminobenzonitrile with aromatic aldehyde in the presence of anhydrous zinc chloride under classical heating and microwave irradiation is described. This is a novel efficient synthetic route of 3,1-benzoxazine cyclic compounds.

Keywords: 3,1-BENZOXAZINE, AROMATIC ALDEHYDE, INTERMEDIATE, CYCLOCONDENSATION

Document Type: Research Article

DOI: https://doi.org/10.3184/030823406777980673

Publication date: 2006-07-01

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  • The Journal of Chemical Research is a monthly journal which has a broad international authorship and publishes research papers and reviews in all branches of experimental chemistry.

    Established in 1977 as a joint venture by the British, French and German chemical societies it maintains the high standards set by the founding societies. Each paper is independently peer reviewed and only carefully evaluated contributions are accepted.

    Recent papers have described new synthetic methods, new heterocyclic compounds, new natural products, and the inorganic chemistry of metal complexes.

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