Skip to main content

Free Content A facile stereoselective synthesis of (E)-2,3-disubstituted allylic alcohols via hydromagnesiation of alkylarylacetylenes

Download Article:
 Download
(PDF 178.4189453125 kb)
 
Hydromagnesiation of alkylarylacetylenes 1 in diethyl ether gave (E)-α-arylvinyl Grignard reagents 2, which reacted with aldehydes or ketones 3 to afford stereoselectively (E)-2,3-disubstituted allylic alcohols 4 in good yields.
No References for this article.
No Supplementary Data.
No Data/Media
No Metrics

Keywords: HYDROMAGNESIATION, ALKYLARYLACETYLENE, VINYL GRIGNARD REAGENT, (E)-ALLYLIC ALCOHOL, STEREOSELECTIVE SYNTHESIS

Document Type: Research Article

Publication date: 2005-02-01

More about this publication?
  • The Journal of Chemical Research is a monthly journal which has a broad international authorship and publishes research papers and reviews in all branches of experimental chemistry.

    Established in 1977 as a joint venture by the British, French and German chemical societies it maintains the high standards set by the founding societies. Each paper is independently peer reviewed and only carefully evaluated contributions are accepted.

    Recent papers have described new synthetic methods, new heterocyclic compounds, new natural products, and the inorganic chemistry of metal complexes.

  • Editorial Board
  • Information for Authors
  • Submit a Paper
  • Subscribe to this Title
  • See all online issues
  • View a demo of this journal
  • Ingenta Connect is not responsible for the content or availability of external websites
  • Access Key
  • Free content
  • Partial Free content
  • New content
  • Open access content
  • Partial Open access content
  • Subscribed content
  • Partial Subscribed content
  • Free trial content
Cookie Policy
X
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more